Having bright, youthful skin is a dream for everyone. However, as time passes and age increases, the skin begins to lose its firmness due to aging. One way to address this is by using natural skin care products like Gravinol KPA-CU.

Gravinol KPA-CU is a highly purified transparent polyphenol extracted from grape seeds using purified water and ethanol. The grape seed contains the highest polyphenols concentration (50%-70% of the total polyphenols in grapes). These high levels of polyphenols in grape seeds help protect genetic material from oxidative damage.

Gravinol KPA-CU offers three notable functions:

1. Anti-Glycation: Inhibits the formation of Advanced Glycation End-products (AGEs)

2. Anti-Oxidation: Scavenges free radicals such as DPPH,

3. Whitening: Inhibits tyrosinase activity to improve skin brightness.

The recommended dosage is 0.01%-1%, suitable for skincare products like lotions, creams, skin milk, face masks, and facial washes.

The concentration of each ingredient required to achieve an activity equivalent to 10 mg/mL of amino guanidine was determined. Surprisingly, only 0.05% Gravinol KPA-CU was able to achieve this. Gravinol KPA-CU has conducted trials to inhibit the formation of AGEs, which impact the skin. Some of the effects include wrinkles, uneven pigmentation, dull complexion, slow healing, and skin complications.

According to "The Inhibition of Advanced Glycation End Products Formation, Gastrointestinal Digestion, Absorption, and Toxicity: A Comprehensive Review", published in the International Journal of Biological Macromolecules, advanced glycation end-products (AGEs) are the final products of non-enzymatic reaction between reducing sugars and amino groups in proteins, lipids, and nucleic acids. The accumulation of AGEs has been implicated as a pathogenic mechanism in various diseases, including diabetes, neuropathy, atherosclerosis, aging, nephropathy, retinopathy, and chronic kidney disease. This process contributes to inflammation, oxidative stress, and structural tissue damage, ultimately leading to chronic vascular complications.

Active ingredients such as vitamins C and E are well-known antioxidants that protect the body from free radicals. A study published by Ankara University highlights Vitamin E as nature's most effective lipid-soluble, chain-breaking antioxidant, protecting cell membranes from free radical-induced damage. Meanwhile, Gravinol KPA-CU has much higher antioxidative activity compared to well-known antioxidants such as Vitamin C and Vitamin E.

So, it protects the body from excessive oxidation. According to the journal The Applications, Neurotoxicity, and Related Mechanism of Gold Nanoparticles, which ScienceDirect published, oxidative stress is a mechanism described as the excessive generation of reactive oxygen species (ROS), which causes an imbalance between the prooxidant and antioxidant levels in the body.

Surprisingly, Gravinol KPA-CU exhibits the highest antioxidant activity compared to vitamins C and E. Furthermore, it protects the body from excessive oxidation, which helps prevent aging and enhances skin beauty.

Gravinol KPA-CU demonstrates strong tyrosinase inhibition, comparable to Kojic Acid at certain concentrations, and superior to Placenta Extract and β-Arbutin in lower dilutions, making it highly effective in promoting skin brightening. This is evidence that testing Gravinol KPA-CU for tyrosinase inhibition can also suppress melanin production.

Gravinol KPA-CU, derived from natural ingredients such as grape seeds combined with purified water and prepared using ethanol, has demonstrated the ability to inhibit tyrosinase, thereby reducing melanin production. Inhibiting melanin production is a common approach to achieving skin lightening.

In conclusion, Gravinol KPA-CU has anti-aging properties with a strong anti-glycation effect that improves skin transparency and elasticity. Its powerful antioxidant properties help prevent wrinkles, dryness, and dark spots, ensuring your skin remains youthful and lightening.

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